HPLC / UV

Purity + net content

HPLC separates the principal compound from detectable impurities, while calibrated UV analysis supports quantitative reporting of the material present. Together, these measurements provide a clear view of both chromatographic purity and net peptide content.

Chromatographic purity profile

The report shows the relative area of the principal chromatographic peak and any detectable related peaks under the stated method conditions.

Principal peak and impurity review

Peak integration is reviewed to distinguish the principal compound response from detectable impurities and method-related signals.

Net content reported in milligrams

A calibrated quantitative response is used to estimate the amount of target material present in the submitted vial.

Method-level results on the final COA

The final certificate records the analytical method, measured values, applicable specifications, and review outcome.

LC–MS

Identity confirmation

LC–MS compares the observed molecular ions with the expected mass of the submitted research compound. The review considers charge states and related spectral evidence to support an identity determination.

Expected molecular-ion comparison

Observed mass-to-charge signals are compared with the theoretical molecular ions expected for the submitted compound.

Charge-state review

Relevant charge states are evaluated together to support interpretation of the molecular-mass evidence.

Observed mass documentation

Key observed ions and the calculated molecular-mass result are documented in the analytical record.

Identity conclusion included on the COA

The certificate provides a clear identity conclusion based on the spectral evidence reviewed by the laboratory.

MICRO / ICP–MS

Safety screening

Optional safety screens can be added to the analytical panel according to the material and research requirements. Available scopes include endotoxin, microbial, sterility, and elemental contamination analysis.

Quantitative endotoxin analysis

A kinetic chromogenic LAL method measures endotoxin and reports the result in Endotoxin Units with assay controls.

Rapid microbial or 14-day sterility screening

Choose a rapid microbial screen or an extended sterility assessment using aerobic and anaerobic incubation.

Heavy-metal screening

A targeted screen checks the sample for regulated elemental contaminants relevant to the requested scope.

Quantitative ICP–MS elemental analysis

ICP–MS can quantify lead, mercury, arsenic, cadmium, and other requested elements in the submitted material.